When a person despises God’s Word, he despises God himself. At the same time he rejects God’s good intention, because God wants to save him through His Word.
Luke 10:16: He that heareth you heareth me; and he that despiseth you despiseth me; and he that despiseth me despiseth him that sent me.
John 8:47: He that is of God heareth God’s words; ye therefore hear them not, because ye are not of God.